Gene
English spotting (En) is an incompletely dominant white spotting gene linked to KIT. One copy gives the broken pattern, white with colored patches; two copies give the mostly white charlie, and rabbits with no copy are solid. Two copies are reported to cause megacolon, a slowed and enlarged large bowel, in a share of rabbits; one copy is not affected.
One copy shows English Spotting (En).
Two copies (charlie) are reported to cause megacolon syndrome: the large bowel slows and enlarges, leading to constipation, weight loss and early death in some rabbits, usually with age. One copy (broken) was not affected.
A rabbit with a solid parent has at most one copy. A ruby-eyed white can carry two copies without showing any spotting.
A marker test is offered for Checkered Giant rabbits. The marker co-segregated with spotting in Checkered Giant families and was consistent with the pattern in three Rhinelander rabbits, but failed in English Spot rabbits. Its interpretation should not be generalized to unvalidated breeds.
Illustrations of typical animals, checked against the sources below. Not photos of DNA-tested animals.
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Guides and articles for English Spotting (En) rabbit owners.
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Calculators, generators, and guides preset for English Spotting (En) rabbit.
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