Ozark Valley Puppies

Ozark Valley Puppies raises Neapolitan mastiffs, English mastiffs, and dogue de Bordeaux on a 20-acre property in Neosho, Missouri, in the southwest corner of the state near Joplin. Melissa Cox and her husband Steve have been breeding these large-breed dogs since 2012, with Neapolitan mastiffs as the breed that first drew them into the mastiff world.

The program operates under oversight from the USDA, the Missouri Department of Agriculture, and AKC, and puppies come with a one-year health guarantee along with current vaccinations and dewormings. A focus on early handling and socialization is central to how the Coxes raise their dogs — they emphasize the difference between puppies raised with hands-on care versus those kept in more confined settings.

Melissa Cox was also among the nine experts consulted for Jordan Honeycutt's book "The Complete Guide to The English Mastiff," reflecting a depth of breed knowledge that extends beyond the kennel. Families across the region looking for Neapolitan mastiff puppies in Missouri or the other mastiff breeds the program produces have found the farm through its long-standing reputation in southwest Missouri.

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